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An Atlas of Neonatal Brain Sonography, 2nd Edition
Clinics in Developmental Medicine No. 182- 183
Authors: Paul Govaert and Linda S. de Vries
ISBN 13:
Mac Keith Press/ Wiley
List Price: $240.00  Hard Cover  419 Pages
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MedicalScienceBooks.com book review of An Atlas of Neonatal Brain Sonography, 2nd Edition:

     The premature infant poses a variety of challenges to the neonatal professionals charged with their care.  Being born before many major developmental milestones have completed puts the infant at immediate risk for several key pathologies, many of which involve brain structure.  Fortunately technological advances over the past few decades have made noninvasive ultrasonography techniques available in the newborn nursery and neonatal intensive care unit.  Taking advantage of the developmental window to the cranial cavity provided by the fontanelles, physicians are able to get ever more detailed views of pathologies that can have fatal or long term consequences if not addressed in a timely manner.  An Atlas of Neonatal Brain Sonography 2nd edition is a guidebook for the interpretation of such images that have been collected from newborns presenting with nearly all the major structural changes detectable with ultrasonographic techniques.

     Divided into a series of nine parts, the text is rationally organized into an opening part on normal anatomy followed by a series of parts which discuss and illustrate congenital and antenatal conditions of both more common and rare occurrence including hydrocephalus and porencephaly.   Following these sections are several more that deal with postnatal conditions including those of significant concern in severely premature and underweight infants such as intraventricular hemorrhage and white matter damage.  The final part is dedicated to a survey of the structural abnormalities detected in infants with a variety of conditions derived from metabolic and infectious etiologies.  Each chapter is complete with a multitude of ultrasonography images which are generally of high quality.  There are only a few images which are somewhat more “grainy” in appearance than might be expected in the process of reproducing these types of images into print, a feat which is admirable given the comprehensive nature of the book and the paucity of examples which likely exist for certain rare conditions.

     Atlases are often also judged upon the content of their textual descriptions in support of their illustrations and photographic offerings.  Many of these atlases, particularly in the medical imaging literature fall quite short on background information and helpful information to keep in mind while reviewing images.  Others become too verbose and thus too comprehensive to consult regularly in the amount of time that can reasonably be spent on one case.  An Atlas of Neonatal Brain Sonography 2nd edition provides the reader with succinct clinical information which increases the ease of use of the book substantially, even for the novice who may be looking at these images for the first time.

     The neonatal medicine specialist will, of course, find this book to be of great use since guidelines dictate quite frequent head ultrasounds of premature infants and others that display any signs of developmental delay.  It is important to have this type of reference available to the clinician as well as the radiologist since the clinician is much more familiar with the complete clinical presentation of the infant.  Many of the pathologies seen on head ultrasound, as with other modalities can be somewhat unimpressive on imaging, and clinical significance is often in question.  It is times such as this that an atlas showcasing clear examples of pathology can be turned to for guidance and pieced together with physical examination and behavioral assessments of the infant to determine the proper course of further treatment.  This book should be kept handy in the newborn nursery, neonatal intensive care, and pediatric clinics following up with children born with any type of congenital or acquired brain injury.


This Atlas covers the entire spectrum of brain disease as studied with ultrasound, illustrated throughout with superb-quality images. It is aimed at neonatologists and radiologists confronted with everyday clinical questions on the neonatal ward. Most newborn brain disorders can be identified with ultrasound; this book will therefore be particularly useful in settings with limited MRI facilities. Prenatal ultrasound specialists will also find it valuable as a postnatal reference in their field of interest. Suggestions for differential diagnosis accompany all the sonographic findings, guiding the clinician in proceeding from an abnormal image to a diagnosis. This second edition of the Atlas has been brought up to date to include the many advances in technique and interpretation that have been made in the past decade. The images have been replaced with new ones of higher quality, and all the line artwork has been standardised and improved.

Neonatologists, radiologists, neuroradiologists with an interest in neonatal ultrasound

Features of New Edition

Second edition updated with a new collection of superb images The only up-to-date comprehensive atlas to focus on neonatal brain ultrasound Covers normal anatomy and neuropathology to aid in interpretation of images

Table of Contents:

Authors' Appointments

Part I  Normal Anatomy

1. Sulci and Gyri
2. Lateral Ventricles
3. Third Ventricle
4. Choroid Plexus
5. Lobar Parenchyma
6. Midline Structures
7. Cisterns
8. Basal Ganglia and Thalamus
9. Brainstem
10. Cerebellum
General References on Normal Anatomy

Part II  Congenital Anomalies

11. Disorders of Neurulation- Neural Tube Defects
12. Cephalocele
13. Hydrocephalus
14. Intracranial Fluid Collections
15. Unilateral Hydrocephalus
16. External Hydrocephalus
17. Disorders of the Corpus Callosum
18. Agenesis and Malformation of the Septum Pellucidum
19. Hamartoma and Accessory Brain
20. Cerebral Hemiatrophy
21. Microcephaly
22. Schizencephaly
23. Disorders of Neuroblast Migration
24. Median Prosencephalic Dysgenesis- Holoprosencephaly
25. Posterior Fossa Anomalies
26. Vascular Anomalies

Part III  Antenatal Brain Damage

27. Antenatal Intracranial Haemorrhage
28. Antenatal Global Forebrain Ischaemia
29. Germinolysis
30. Hydranencephaly
31. Porencephaly
32. Multicystic Ecephalopathy
33. Choroid Plexus Pseudocyst
34. Moebius Sequence
35. Twin (Multiplet)- Associated Antepartum Brain Damage
36. Striatal Vasculopathy

Part IV  Fetopathy

37. Fetopathy (Congenital Non-Bacterial Brain Infection)

Part V  Haemorrhage

38. GMH/IVH: Haemorrhage into Preterm Germinal Matrix and Ventricle
39. Posthaemorrhagic Ventricular Dilatation
40. Epidural Haematoma
41. Subdural Haematoma
42. Lobar Cerebral Haemorrhage
43. Cerebellar Haemorrhage
44. Haemorrhage into the Thalamus, Basal Ganglia and Ventricle (Deep Venous Thrombosis)
45. Term Intraventricular Haemorrhage (IVH)
46. Subarachnoid Haematoma and Non-Accidental Injury

Part VI  Asphyxia

47. Asphyxia

Part VII  Ischaemic Stroke

48. Arterial Ischaemic Stroke
49. Middle Cerebral Artery Stroke
50. Internal Carotid Artery Stroke
51. Anterior Cerebral Artery Stroke
52. Posterior Cerebral Artery Stroke
53. Watershed Injury
54. Anterior Choroidal Artery Stroke
55. Perforator Stroke
56. Focal Infarction of Brainstem, Cerebellum and Spinal Cord
57. Sinus Thrombosis

Part VIII  Preterm White Matter Injury

58. Preterm White Matter Injury

Part IX  Miscellaneous

59. Kernicterus
60. Hypoglycaemia
61. Inborn Errors of Metabolism
62. Hypertensive Encephalopathy
63. Bacterial Meningitis, Ventriculitis
64. Air Embolism
65. Chaniocerebral Erosion
66. Brain Perforation
67. Neuroectodermal Disorders
68. Leukodystrophy
69. Neonatal Brain Tumour


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