Preface
1. Burden of Ischemic Heart Disease
Erling Falk, Prediman K. Shah and Pim J. de Feyter
2. Anatomy of the Heart
Coronary arteries
Saibal Kar
Myocardium
Saibal Kar and Prediman K. Shah
Conduction system
Miguel Valderrábano and C. Thomas Peter
3. Physiology of the Heart
Coronary circulation
Dirk J.G.M. Duncker and Daphne Merkus
Myocardium and determinants of oxygen demand
Henry Gewirtz and Ahmed Tawakol
Conduction system
Peter Lukac and Anders Kirstein Pedersen
4. Pathophysiology of Myocardial Ischemia
Coronary artery anomalies
Allen J. Taylor and Renu Virmani
Anerobic myocardial metabolism
Frans C. Visser
Collateral development
Steve Lee, Rajendra Makkar and William Ganz
Preconditioning, stunning, and hibernation
Sriram Padmanabhan, Howard Lewin and Prediman K. Shah
5. Myocardial Ischemia: Compromised Supply
Atherothrombosis
Jens Flensted Lassen and Erling Falk
Coronary vasoconstriction and spasm
Filippo Crea and Gaetano A. Lanza
Nonatherothrombotic coronary artery disease
Ulrik Baandrup and Ingrid Bayer Kristensen
Microvascular disease
Hans Erik Bøtker
Systemic causes of compromised supply
Kavita Kumar
Transplant vasculopathy
Samir R. Kapadia and E. Murat Tuzcu
Traumatic coronary artery disease
Juan A. Asensio, Eric J. Kuncir, Patrizio Petrone and Tamer Karsidag
6. Myocardial Ischemia: Morbid Demand
Cardiac hypertrophy
K-Raman Purushothaman, William N. O'Connor, Dario Echeverri and Pedro R. Moreno
Systemic causes of increased demand
Kavita Kumar
7. Detection of Coronary Artery Disease
Diagnostic coronary angiography
Jens Knudsen and Ulrik Abildgaard
Quantitative coronary arteriography
Johan H.C. Reiber, Joan C. Tuinenburg, Gerhard Koning and Bob Goedhart
Magnetic resonance coronary angiography
Robert Jan M. van Geuns
Noninvasive multi-slice spiral computed tomography
Koen Nieman and Pim J. de Feyter
Intracoronary ultrasound
Nico Bruining
Coronary angioscopy
Yasumi Uchida
Intracoronary Doppler flow
M. Voskuil and J.J. Piek
Endothelial dysfunction
K.E. Sørensen and D.S. Celermajer
Electron-beam computed tomography: coronary calcium
Axel Schmermund, Stefan Möhlenkamp and Raimund Erbel
Vulnerable atherosclerotic plaques
Erling Falk, Johannes A. Schaar and Morteza Naghavi
8. Detection of Myocardial Ischemia and Infarction
Electrocardiography
K.S. Channer
Exercise testing
Jonathan M. Hill and Adam D. Timmis
Continuous vectorcardiographic monitoring
Bjarne Linde Nørgaard
Electrophysiology
Anders Kirstein Pedersen
Echocardiography
Henrik Egeblad
Myocardial scintigraphy
Anne Kaltoft and Morten Bøttcher
Positron emission tomography
Morten Bøttcher
Magnetic resonance imaging
Won Yong Kim and Eike Nagel
Computed tomography
Sriram Padmanabhan, Matthew J. Budoff and Prediman K. Shah
Electromechanical mapping
Hans Erik Bøtker
Invasive hemodynamic monitoring
Christian Lindskov Christiansen and Erik Sloth
Biochemical marker
Jan Ravkilde
9. Stable Ischemic Syndromes
Stable angina pectoris
Jens Erik Nielsen-Kudsk
Prinzmetal's variant angina
Joseph Aragon and Prediman K. Shah
Cardiac syndrome X
Hans Erik Bøtker
10. Acute Coronary Syndromes
Non-ST elevation acute coronary syndromes
R.J. de Winter
Acute myocardial infarction with ST segment elevation
John K. French and Harvey D. White
Out-of-hospital cardiac arrest and sudden cardiac death
R.W. Koster
Triggering of acute coronary syndromes
Christian J. Mussap, James E. Muller and Geoffrey H. Tofler
Ischemic Heart Disease
11. Acute Myocardial Infarction: Complications
Cardiogenic shock
Søren Boesgaard and Jan Aldershvile
Mechanical complications
Henrik Egeblad
Arrhythmias complicating acute myocardial infarction
Miguel Valderrábano and C. Thomas Peter
Other complications
Ira Perry and Saibal Kar
12. Acute Myocardial Infarction: Special Problems
Right ventricular acute myocardial infarction
Henning Rud Andersen
Thrombolysis or primary angioplasty?
Henning Rud Andersen
Reperfusion injury
Miguel Valderrábano and William Ganz
Downstream (micro)embolization, slow flow, and no reflow
Erling Falk and Leif Thuesen
Age and acute myocardial infarction
Wilbert S. Aronow
Gender differences in acute myocardial infarction
Johan Herlitz
Diabetes and acute myocardial infarction
Joseph Aragon and Prediman K. Shah
Smoking
Morten Bøttcher
Acute myocardial infarction in normal coronary arteries
Ira Perry and Saibal Kar
13. Heart Attack: Management Strategy
Prehospital
Jens Flensted Lassen
Emergency Department
Kristian Thygesen and Joseph S. Alpert
Coronary Care Unit
Kristian Thygesen and Joseph S. Alpert
Posthospital
Mogens Lytken Larsen
14. Silent Myocardial Ischemia
Hans Mickley
15. Chronic Arrhythmias and Conduction Disorders
Anders Kirstein Pedersen
16. Left Ventricular Dysfunction
Heart failure
John G.F. Cleland, Nikolay Nikitin, Farqad Alamgir and Andrew Clark
Ischemic cardiomyopathy, hibernation, and viability
Arend F.L. Schinkel, Jeroen J. Bax and Don Poldermans
17. Percutaneous Coronary Intervention
Indications, procedure, and technique
Leif Thuesen
Results and complications
Sjoerd H. Hofma and Pim J. de Feyter
Late restenosis
Benno J. Rensing
18. Coronary Artery Bypass Graft Surgery
Procedures and indications
Matthew J. Price
Complications and outcomes
Matthew J. Price and Steven S. Khan
19. Ischemic Heart Disease: Special Problems
Women and hormones
Steve Lee and Steven S. Khan
Diabetic atherogenic dyslipidemias
Allan D. Sniderman
Revascularization: percutaneous coronary intervention versus coronary artery bypass grafting
David Tüller and Bernhard Meier
Allograft coronary artery disease
Henrik Egeblad
Chronic refractory angina
Michael C. Kim and Samin K. Sharma
Ethnicity and cardiovascular disease
Stephanie Ounpuu and Salim Yusuf
Cardiovascular disease in chronic kidney disease
Daniel E. Weiner and Mark J. Sarnak
20. Primary Prevention
Steve Lee and Noel Bairey Merz
21. Genetics of Ischemic Heart Disease
Anne Tybjærg-Hansen
22. Stem Cell Therapy in Acute Myocardial Infarction
Jens Kastrup
23. Guidelines and Recommendations
Steen E. Husted and Birgitte K. Ziegler
References
Index