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Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Second Edition
Authors:  Eric J. Nestler, Steven E. Hyman, Robert Malenka
Pages:  498    Paperback
ISBN 10: 0071481273
ISBN 13: 9780071481274
McGraw-Hill     October 27, 2008
List Price:  $54.95
 

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MSB Book Review by Joseph V. Russo, MS:

     Students and non-specialists often find the complexities of the infrastructure of the nervous system compounded by the intricacies of the myriad chemical events which take place in its functioning.  This all-too-often results in a view of the nervous system as a “black box”, the integrated function of which eludes all but the most dedicated.  Many neurology texts, even those intended for beginners, seem to foster this attitude by the inclusion of non-discriminate detail that doesn’t add to the integrative understanding of the field.

     Molecular neuropharmacology: A foundation for clinical neuroscience 2nd edition offers a straightforward approach which will be appreciated by those in need of an introduction to the pharmacology of neuroactive agents and general neurophysiology.  This is a result of the foresight of the editors, not only in arranging the material into layers of complexity, but also taking the next step and being sure that there is continuity throughout.  For example, drugs and receptors introduced in the opening chapters of the book often appear in several sections of the text including those illustrating their role in complex processes.  This allows the student to become familiar with a handful of concepts and see them through to application rather than “having the rug pulled out from under them” and having to learn new sets of unrelated information in each section of the text.

     The text is also visually appealing as it contains 300 high quality color illustrations which display the same qualities of conciseness and relevance that seem to have guided the production of this book.  Impressively, this is all contained in less than 500 pages, making it a practical and user friendly option for instructors to use in their semester courses. Students will find this text invaluable as an introduction to neuroscience and experienced professionals will find it a refreshing overview.

From the Publisher:  

 

Turn to the classic primer of molecular neuroscience for a complete understanding of nervous system function and it's relationship to human neurologic disorders

Molecular Neuropharmacology offers a clear, thorough explanation of the molecular functioning of the nervous system in normal and disease states. More than three hundred concept-clarifying full-color illustrations along with didactic text boxes provide an in-depth understanding of nerve cell receptors, their effectors and second messenger targets, and the molecular genetics that are often impacted by these systems. You will also learn how malfunction of these molecular systems relates to human disease and the corresponding medical treatment.

Molecular Neuropharmacology is the most relevant, well-written resource available to help you make the connection between neuropharmacology and clinical neuroscience.

Numerous figures and didactic boxes help you understand and remember complex subject matter for efficient, on-the-spot review. The book's all-inclusive, high-yield coverage includes:

 

  • The fundamentals of neuropharmacology
  • Neural substrates of drug action
  • The neuorpharmacology of specific functions and disorders--encompassing control of movement, mood and emotion, memory and dementia, and other vital areas
  • NEW! A streamlined redesign that makes the book even more practical and accessible than ever
  • NEW! More illustrations--all 300 now in full color!

 

Table of contents

Molecular Neuropharmacology: A Doundation for Clinical Neuroscience, 2/e
Fundamentals of Neuropharmacology
1. Neurons and Glia
2. Synaptic Transmission
3. Signal Transduction Pathways
4. Signaling to the Nucleus
Neural Substrates of Drug Action
5. Excitatory and Inhibitory Amino Acids
6. Catecholamines
7. Serotonin, Acetylcholine, and Histamine
8. Neuropeptides and Purines
9. Neurotropic Factors
Neuropharmacology of Specific Functions and Disorders
10. Autonomic Nervous System
11. The Neuroendocrine System
12. Control of Movement
13. Mood and Emotion
14. Reinforcement and Addiction
15. Higher Cognitive Function and Psychosis
16. Sleep, Arousal and Attention
17. Pain
18. Memory and Dementia
19. Seizures and Stroke

Biographical note

Eric J. Nestler, MD, is professor and chairman of the Department of Psychiatry and the Center for Basic Neuroscience at the Southwestern Medical School, Graduate School of Biomedical Science in Dallas, Texas.
Stephen E. Hyman, MD, is provost of Harvard University and professor of neurobiology at Harvard Medical School.
Robert C. Malenka, MD, Ph.D., is Pritzker Professor of Psychiatry & Behavioral Sciences at Stanford University.

 

 
 
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