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The Evidence-Based Guide to Antidepressant Medications
Editor; Anthony J. Rothschild, MD
ISBN 13:
978-1-904455-74-5
American Psychiatric Publishing
List Price: $69  Member Price $55  Member in Training $51.65   404 Pages  Soft Cover 
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   MedicalScienceBooks.com Medical Book Review:

     The antidepressants are consistently among the most prescribed drug classes and have been nearly since their discovery several decades ago.  Widespread use has uncovered a number of side effects intrinsic to the class and when used in conjunction with other common agents.  Because of these facts and the ever expanding patient market for these drugs, the development of more effective and safer formulations has been the driving force for much pharmaceutical research.   The Evidence-Based Guide to Antidepressant Medications condenses the large body of literature that exists on these medicines and helps the practitioner make rational treatment decisions for their patients.

     Each chapter is focused on a specific patient population either suffering from a particular disorder or condition such as anxiety or which represent a specific class of patients such as those that are pregnant or elderly.  Disease based chapters begin with a general discussion of the disorder followed by a short description of the proposed mechanism of action by which antidepressants might improve the quality of life of the patient.  Refreshingly, for an evidence-based publication, there are not multiple bulky tables of research article summaries.  Instead there much more focused tables consisting of fewer studies that were selected for their unique contributions to answering a clinical question.  This improves the flow of the chapters and keeps the reader thinking about the overall issue at hand rather than trying to find a definitive conclusion from dozens of listed studies, many of which contain fatal errors in their conduction.

     Key clinical features are listed at the end of each section which provide a nice review of the material in the chapters and further turn the readerís attention to the main points rather than a rundown of a list of research findings.  For example in the chapter focused on prescribing antidepressants to children and adolescents the points that psychotherapy should be first considered and attentive monitoring should be given when medication is used are well made.   Another important chapter addresses the questions about safe treatment during pregnancy given the possibility of side effects not only for the woman but her unborn child as well. 

     All in all, The Evidence-Based Guide to Antidepressant Medications provides an up to date source of information from which the busy psychiatric consultant can draw from as they see patients in and outside the hospital.  It is comprehensive enough to cover the unique circumstances surrounding nearly any patient encounter which might require a antidepressant prescription.

Ratings (1-10 , 10 being the highest):

Overall Rating:

8.6

Authorís objectives met:

9

Comprehensiveness:

9
Organization of information: 9
Significant number of illustrations: 5
Suitable for intended audience: 10
Overall presentation: 8
Quality of illustrations: na
Usefulness of book:   9
Value: 10
Writing style: 8

Description:

The second book in the Evidence-Based Guides series, The Evidence-Based Guide to Antidepressant Medications, provides a clear reference to the current knowledge and evidence base for the use of antidepressants among a variety of patients across a wide range of disorders. Chapters within this guide are authored by experts in their respective areas of practice, and synthesize a large amount of medical literature into a comprehensive, yet understandable, concise, reader-friendly guide. Each chapter covers both the FDA-approved and off-label use of antidepressant medications and the evidence base for their use. Each chapter also features useful tables pertaining to specific topics, such as summaries of uses and efficacy, and important clinical pearls of wisdom in the Key Clinical Concepts. Topics covered in chapters within this text include:
  • Use of selective serotonin reuptake inhibitors, MAOIs, and tricyclic antidepressants in major depressive disorder, bipolar depression, psychotic depression, and treatment-resistant depression.
     
  • Acute management of anxiety disorders, obsessive-compulsive disorder, and specific phobias through antidepressant use.
     
  • Use of antidepressant medication in medically ill patients, such as those with cardiovascular, pulmonary, gastrointestinal, renal, and endocrine diseases, as well as cancer, chronic pain, HIV, burns and hospital-based trauma.
     
  • Developmental considerations necessary to keep in mind when prescribing antidepressants to children and adolescents, along with an outline of controlled studies and their special attention to safety.
     
  • Medication management in geriatric patients, including antidepressant use among depressed elderly patients with dementia, stroke, or Parkinsonís disease.
     
  • Risks and benefits of prescribing antidepressants during pregnancy and lactation.

Together, the authors have synthesized a large amount of medical literature into a comprehensive, yet understandable, concise, reader-friendly guide. The Evidence-Based Guide to Antidepressant Medications is a must-have reference for psychiatrists and other practicing clinicians, residents in training, psychiatric nurses, social workers and researchers.


Table of Contents:

Introduction.

Unipolar and bipolar depression.

Anxiety disorders.

Schizophrenia and schizoaffective disorder.

Personality disorders.

Substance-related disorders.

Use of antidepressants in children and adolescents.

Use of antidepressants in geriatric patients.

Use of antidepressants in the medically ill patients.

Use of antidepressants during pregnancy and lactation.

Use of antidepressants in patients receiving nursing care.

Index.

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